Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
WT1 | P19544 | WT1 transcription factor | Nucleic acid binding | 1.00 | 0.422 | 0.808 |
VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
SLC22A12 | Q96S37 | solute carrier family 22 member 12 | Transporter | 1.7E-13 | 0.647 | 0.538 |
SEM1 | P60896 | SEM1 26S proteasome complex subunit | 1.8E-02 | 0.633 | 0.538 | |
S100A2 | P29034 | S100 calcium binding protein A2 | Calcium-binding protein | 5.8E-05 | 0.603 | 0.577 |
RPL21P4 | ribosomal protein L21 pseudogene 4 | 1.000 | 0.192 | |||
RNU1-4 | RNA, U1 small nuclear 4 | 0.626 | 0.577 | |||
RB1 | P06400 | RB transcriptional corepressor 1 | Nucleic acid binding | 1.00 | 0.444 | 0.885 |
RASSF7 | Q02833 | Ras association domain family member 7 | 2.3E-11 | 0.621 | 0.538 | |
RAD52 | P43351 | RAD52 homolog, DNA repair protein | Nucleic acid binding | 7.1E-11 | 0.610 | 0.654 |
RAD51D | O75771 | RAD51 paralog D | 1.1E-09 | 0.674 | 0.385 | |
RAD51C | O43502 | RAD51 paralog C | 6.2E-14 | 0.533 | 0.692 | |
RAD51B | O15315 | RAD51 paralog B | 2.1E-15 | 0.556 | 0.769 | |
RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
RAD50 | Q92878 | RAD50 double strand break repair protein | 3.4E-27 | 0.556 | 0.808 | |
PTEN | P60484 | phosphatase and tensin homolog | Enzyme | 0.26 | 0.305 | 0.923 |
PRSS1 | P07477 | serine protease 1 | Enzyme | 4.1E-11 | 0.563 | 0.692 |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
PMS1 | P54277 | PMS1 homolog 1, mismatch repair system component | Nucleic acid binding | 1.3E-17 | 0.569 | 0.654 |
PARP1 | P09874 | poly(ADP-ribose) polymerase 1 | 3.3E-04 | 0.389 | 0.923 | |
PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
OLA1 | Q9NTK5 | Obg like ATPase 1 | Enzyme modulator | 5.8E-02 | 0.780 | 0.269 |
NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
NOTCH3 | Q9UM47 | notch receptor 3 | 0.41 | 0.435 | 0.808 |